Chronic inflammatory diseases

• You are a healthy Caucasian male or female
• You are between 18 and 55 years old
• You do not smoke
• Your Body Mass Index (BMI) is between 18 and 30 kg/m2.
• You can only participate in this study if you have not participated in another study within 12 weeks prior to the first drug administration in this study.
• As a male you are only allowed to participate in this study if:
  • You will use a condom and your fertile female partner uses an intrauterine device (including copper ones) or a hormonal contraceptive;
  • or you were vasectomized;
  • or your female partner is at least 12 months postmenopausal (without menstrual periods) or surgically sterilized;
  • or you are completely abstinent (not sexually active) during the study in accordance with your lifestyle;
  • or you are only sexual active with a male.
• As a female you are only allowed to participate in this study if:
  • You have been postmenopausal and you have not menstruated for a period of 12 months before screening
  • You were surgical sterilized (both ovaries or fallopian tubes have been removed, or removal of the uterus)
• To determine if you are eligible to participate in this study, you will undergo a medical screening in  Groningen. This will take place within 6 weeks before the clinical start.

Since the metabolism of the drug in the body can vary based on ethnicity, only Caucasian volunteers can participate. This means that you belong to or are descended from one of the original populations of Europe, the Middle East, North Africa, or the Indian subcontinent

Vergütung (auf Englisch)